BDBM50591363 CHEMBL5170275

SMILES Cc1cccc(c1)C1NC(=O)c2c(Cl)cccc2N1

InChI Key InChIKey=OBDBCXGMLSMARG-UHFFFAOYSA-N

Data  1 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50591363   

TargetProtein polybromo-1(Homo sapiens (Human))
Medical College Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50591363(CHEMBL5170275)
Affinity DataIC50:  260nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
TargetProtein polybromo-1(Homo sapiens (Human))
Medical College Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50591363(CHEMBL5170275)
Affinity DataKd:  3.90E+3nMAssay Description:Binding affinity to His-TEV-tagged human PBRM1 BD5 transfected in Escherichia coli BL21 (DE3) assessed as dissociation constant at 30 uM by ITC analy...More data for this Ligand-Target Pair
TargetProtein polybromo-1(Homo sapiens (Human))
Medical College Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50591363(CHEMBL5170275)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to His-TEV-tagged recombinant human PBRM1 BD2 transfected in Escherichia coli BL21 (DE3) assessed as dissociation constant at 30 uM ...More data for this Ligand-Target Pair