BDBM50591380 CHEMBL5180611

SMILES Cc1cccc(c1)C1NC(=O)c2c(Br)cccc2N1

InChI Key InChIKey=PXWIXTCIXZCREB-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50591380   

TargetProtein polybromo-1(Homo sapiens (Human))
Medical College Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50591380(CHEMBL5180611)
Affinity DataIC50:  160nMAssay Description:Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia col...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein polybromo-1(Homo sapiens (Human))
Medical College Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50591380(CHEMBL5180611)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to His-TEV-tagged human PBRM1 BD5 transfected in Escherichia coli BL21 (DE3) assessed as dissociation constant at 30 uM by ITC analy...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein polybromo-1(Homo sapiens (Human))
Medical College Of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50591380(CHEMBL5180611)
Affinity DataKd:  4.40E+3nMAssay Description:Binding affinity to His-TEV-tagged recombinant human PBRM1 BD2 transfected in Escherichia coli BL21 (DE3) assessed as dissociation constant at 30 uM ...More data for this Ligand-Target Pair
In DepthDetails PubMed