BDBM50591914 CHEMBL5208315

SMILES CS(=O)(=O)Nc1ccc(cn1)-c1cn(nn1)[C@@H]1CN[C@@H](C1)C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=AKFZSHPZKXBMCK-BBRMVZONSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50591914   

TargetTyrosine-protein kinase ABL1 [T315I]/Breakpoint cluster region protein(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50591914(CHEMBL5208315)
Affinity DataIC50:  111nMAssay Description:Inhibition of Bcr-Abl T315I mutant (unknown origin) incubated for 1 hr in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50591914(CHEMBL5208315)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of wild type Bcr-Abl (unknown origin) incubated for 1 hr in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed