BDBM50592047 CHEMBL5171843

SMILES CN1CCN(CC1)c1ccc(Nc2nc(N)c(s2)C(=O)c2c(F)cccc2C(F)(F)F)cc1

InChI Key InChIKey=QVZIQCVGMKXLJK-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50592047   

TargetCyclin-dependent kinase 11A(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50592047(CHEMBL5171843)
Affinity DataKd:  170nMAssay Description:Binding affinity to wild type human partial length CDK11A (D391 to K730 residues) expressed in bacterial expression system assessed as dissociation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 11A(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50592047(CHEMBL5171843)
Affinity DataIC50:  900nMAssay Description:Inhibition of N-terminus or C-terminus NLuc fused CDK11A (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50592047(CHEMBL5171843)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant full length His-tagged CDK9/Cyclin T1 expressed in Baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50592047(CHEMBL5171843)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK6/Cyclin D1 expressed in Baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50592047(CHEMBL5171843)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant full length GST-tagged CDK4/Cyclin D1 expressed in Baculovirus expression system by Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed