BDBM50592356 CHEMBL4458793

SMILES Nc1c(F)c(NCc2ccc(cc2)C(F)(F)F)ccc1NC(=O)OC1CC1

InChI Key InChIKey=ABYIXDBMGLFCSO-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50592356   

TargetPotassium voltage-gated channel subfamily KQT member 2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50592356(CHEMBL4458793)
Affinity DataEC50:  3.03E+3nMAssay Description:Agonist activity at Kv7.2 (unknown origin) assessed as shifting of voltage dependent activation to more negative potentials by SyncroPatch assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily KQT member 5(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50592356(CHEMBL4458793)
Affinity DataEC50:  3.78E+3nMAssay Description:Agonist activity at Kv7.5 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50592356(CHEMBL4458793)
Affinity DataEC50:  910nMAssay Description:Agonist activity at Kv7.4 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily KQT member 2/3(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50592356(CHEMBL4458793)
Affinity DataEC50:  18nMAssay Description:Agonist activity at Kv7.2/3 (unknown origin) expressed in CHO cells co-expressing GFPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed