BDBM50593116 CHEMBL5173493

SMILES CCNNC(=O)c1ccc(CN2c3ccccc3C=Cc3ccncc23)cc1

InChI Key InChIKey=ZNRZSMMDQXGEGA-UHFFFAOYSA-N

Data  4 KI  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50593116   

TargetHistone deacetylase 6(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataKi:  3nMAssay Description:Binding affinity to recombinant HDAC6 (unknown origin) assessed as inhibition constant using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr f...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataKi:  430nMAssay Description:Binding affinity to recombinant HDAC3 (unknown origin) assessed as inhibition constant using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr f...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataKi:  875nMAssay Description:Binding affinity to recombinant HDAC1 (unknown origin) assessed as inhibition constant using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr f...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataKi:  1.04E+3nMAssay Description:Binding affinity to recombinant HDAC2 (unknown origin) assessed as inhibition constant using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr f...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant HDAC7 (unknown origin) using Boc-Lys (trifluoroacetyl) AMC as substrate preincubated for 1 hr followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) using Boc-Lys (trifluoroacetyl) AMC as substrate preincubated for 1 hr followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant HDAC9 (unknown origin) using Boc-Lys (trifluoroacetyl) AMC as substrate preincubated for 1 hr followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataIC50:  461nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 0 min followed by substrate addition and mea...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataIC50:  257nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 15 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 60 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataIC50:  51nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 120 mins followed by substrate addition and ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant HDAC5 (unknown origin) using Boc-Lys (trifluoroacetyl) AMC as substrate preincubated for 1 hr followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of recombinant HDAC4 (unknown origin) using Boc-Lys (trifluoroacetyl) AMC as substrate preincubated for 1 hr followed by substrate additio...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataIC50:  1.03E+3nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Ocean University Of China

Curated by ChEMBL
LigandPNGBDBM50593116(CHEMBL5173493)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails PubMed