BDBM50594024 CHEMBL5174780

SMILES Cc1ccc(NC(=O)c2ccc(NC(=O)N3CCN(CC3)C(=O)c3cc(Cc4n[nH]c(=O)c5ccccc45)ccc3F)cc2)cc1

InChI Key InChIKey=PBOOUBWKFXDCRA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50594024   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50594024(CHEMBL5174780)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of PARP-1 (unknown origin) using biotinylated NAD+ as substrate incubated for 45 mins in the presence of deoxy-oligonucleotide by micropla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50594024(CHEMBL5174780)
Affinity DataIC50:  14nMAssay Description:Inhibition of TNKS2 (unknown origin) using biotin-NAD+ as substrate incubated for 1 hr in the presence of deoxy-oligonucleotide by ELISA analysis rel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50594024(CHEMBL5174780)
Affinity DataIC50:  39nMAssay Description:Inhibition of TNKS1 (unknown origin) using biotin-NAD+ as substrate incubated for 1 hr in the presence of deoxy-oligonucleotide by ELISA analysis rel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed