BDBM50594075 CHEMBL5186789

SMILES OC(=O)c1c(NC(=O)c2cc(F)ccc2F)scc1-c1ccc(Cl)cc1

InChI Key InChIKey=RZXHOVMOLRFUCA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50594075   

TargetAnoctamin-1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50594075(CHEMBL5186789)
Affinity DataIC50:  24nMAssay Description:Inhibition of YFP tagged ANO1 (unknown origin) expressed in FRT cells incubated for 24 hrs by fluorescence plate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAnoctamin-2(Homo sapiens)
Peking University

Curated by ChEMBL
LigandPNGBDBM50594075(CHEMBL5186789)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human ANO2 expressed in HEK293 cells incubated for 5 mins by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50594075(CHEMBL5186789)
Affinity DataIC50: >3.00E+4nMAssay Description:Cardiotoxicity against human ERG expressed in HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails PubMed