BDBM50594505 CHEMBL5177316
SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1
InChI Key InChIKey=IKEQMDLYPNVQGH-WGQQHEPDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50594505
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataEC50: 1.20E+3nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataEC50: 1.48E+3nMAssay Description:Agonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human P2X7R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Antagonist activity at human P2X7R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Antagonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 2.63E+4nMAssay Description:Antagonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Antagonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Antagonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr foll...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Antagonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
TargetP2X purinoceptor 7(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataEC50: <1.00E+5nMAssay Description:Agonist activity at human P2X7R expressed in HEK293 cells assessed as reduction in YO-PRO-1 iodide dye uptake preincubated for 30 mins followed by YO...More data for this Ligand-Target Pair