BDBM50594792 CHEMBL5181028

SMILES COc1cc(\C=C2/N=C(Nc3ccc(cc3)N3CCCCC3)NC2=O)ccc1O

InChI Key InChIKey=RXBPHXFEWBJMNT-AQTBWJFISA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50594792   

TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Sus scrofa)
Manros Therapeutics & Perha Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50594792(CHEMBL5181028)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of porcine brain GSK-3alpha/beta using YRRAAVPPSPSLSRHSSPHQpSEDEEE as substrate incubated for 30 mins in presence of ATP by scintillation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity protein kinase CLK4(Mus musculus)
Manros Therapeutics & Perha Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50594792(CHEMBL5181028)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of GST-fused mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Manros Therapeutics & Perha Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50594792(CHEMBL5181028)
Affinity DataIC50:  750nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity protein kinase CLK2(Mus musculus)
Manros Therapeutics & Perha Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50594792(CHEMBL5181028)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse recombinant GST-fused CLK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Manros Therapeutics & Perha Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50594792(CHEMBL5181028)
Affinity DataIC50:  297nMAssay Description:Antagonist activity at CP-55940-activated CB1 receptor (unknown origin) by beta-arrestin assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Manros Therapeutics & Perha Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50594792(CHEMBL5181028)
Affinity DataIC50:  410nMAssay Description:Inhibition of GST-fused human recombinant DYRK1B expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Manros Therapeutics & Perha Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50594792(CHEMBL5181028)
Affinity DataIC50:  410nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Homo sapiens (Human))
Manros Therapeutics & Perha Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50594792(CHEMBL5181028)
Affinity DataIC50:  300nMAssay Description:Inhibition of GST-fused human recombinant DYRK3 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Manros Therapeutics & Perha Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50594792(CHEMBL5181028)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of human recombinant Pim1 expressed in Escherichia coli using histone H1 as substrate incubated for 30 mins in presence of ATP by scintill...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Manros Therapeutics & Perha Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50594792(CHEMBL5181028)
Affinity DataIC50:  280nMAssay Description:Inhibition of GST-fused human recombinant DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in prese...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed