BDBM50595368 CHEMBL5191615

SMILES COc1cc2c(NC3CCN(CC3)C(C)C)nc(NC(=O)C=C)nc2cc1OCCCN1CCCC1

InChI Key InChIKey=JBMUWBUCVSKHLE-UHFFFAOYSA-N

Data  2 IC50  2 Kd

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50595368   

TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50595368(CHEMBL5191615)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of human G9a (913 to 1193 residues) using H3 peptide as substrate measured upto 45 mins in presence of SAM cofactorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50595368(CHEMBL5191615)
Affinity DataKd:  790nMAssay Description:Binding affinity to human G9a (913 to 1193 residues) assessed as dissociation constant by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50595368(CHEMBL5191615)
Affinity DataKd:  790nMAssay Description:Binding affinity to human GLP (982 to 1266 residues) assessed as dissociation constant by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50595368(CHEMBL5191615)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human GLP (982 to 1266 residues) using H3 peptide as substrate measured upto 45 mins in presence of SAM cofactorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB