BDBM50595370 CHEMBL5189737
SMILES CCC(=O)Nc1cc(NC2CCN(CC2)C(C)C)c2cc(OC)c(OCCCN3CCCC3)cc2n1
InChI Key InChIKey=FGAGTVKUPJXOMV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50595370
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataKd: 48nMAssay Description:Binding affinity to human G9a (913 to 1193 residues) assessed as dissociation constant measured after 1 hr by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 151nMAssay Description:Inhibition of human GLP (982 to 1266 residues) using H3 peptide substrate preincubated for 5 mins followed by SAM addition measured after 10 mins by ...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 211nMAssay Description:Inhibition of human G9a (913 to 1193 residues) using H3 peptide substrate preincubated for 5 mins followed by SAM addition measured after 10 mins by ...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Icahn School Of Medicine At Mount Sinai
Curated by ChEMBL
Affinity DataKd: 16nMAssay Description:Binding affinity to human GLP (982 to 1266 residues) assessed as dissociation constant measured after 1 hr by isothermal titration calorimetry methodMore data for this Ligand-Target Pair