BDBM50595569 CHEMBL5184829
SMILES [H][C@@]12CC[C@@]([H])(C1)[C@]1(ON=C(c3cccnc3)[C@@]21[H])C(=O)Nc1ccc2[nH]ncc2c1
InChI Key InChIKey=RGHYMBULABJHQT-OKNMBPCOSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50595569
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of human CYP11B2 expressed in Chinese hamster V79 MZh cells using [14C]-deoxycorticosteron as substrate measured after 6 hrs by phosphoima...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H]-androstenedione as substrateMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of human CYP11B1 expressed in Chinese hamster V79 MZh cells using [14C]-deoxycorticosteron as substrate measured after 6 hrs by phosphoima...More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of rat CYP11B1More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human hepatic recombinant CYP2C9 using cocktail of substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human hepatic recombinant CYP2C19 using cocktail of substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human hepatic recombinant CYP2D6 using cocktail of substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human hepatic recombinant CYP3A using cocktail of substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Guangzhou University Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human hepatic recombinant CYP1A2 using cocktail of substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair