BDBM50595569 CHEMBL5184829

SMILES [H][C@@]12CC[C@@]([H])(C1)[C@]1(ON=C(c3cccnc3)[C@@]21[H])C(=O)Nc1ccc2[nH]ncc2c1

InChI Key InChIKey=RGHYMBULABJHQT-OKNMBPCOSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50595569   

TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50595569(CHEMBL5184829)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of human CYP11B2 expressed in Chinese hamster V79 MZh cells using [14C]-deoxycorticosteron as substrate measured after 6 hrs by phosphoima...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAromatase(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50595569(CHEMBL5184829)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human placental microsome CYP19 using [1beta-3H]-androstenedione as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50595569(CHEMBL5184829)
Affinity DataIC50:  9nMAssay Description:Inhibition of human CYP11B1 expressed in Chinese hamster V79 MZh cells using [14C]-deoxycorticosteron as substrate measured after 6 hrs by phosphoima...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50595569(CHEMBL5184829)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
Guangzhou University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50595569(CHEMBL5184829)
Affinity DataIC50:  25nMAssay Description:Inhibition of rat CYP11B1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50595569(CHEMBL5184829)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human hepatic recombinant CYP2C9 using cocktail of substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50595569(CHEMBL5184829)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human hepatic recombinant CYP2C19 using cocktail of substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50595569(CHEMBL5184829)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human hepatic recombinant CYP2D6 using cocktail of substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50595569(CHEMBL5184829)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human hepatic recombinant CYP3A using cocktail of substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Guangzhou University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50595569(CHEMBL5184829)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human hepatic recombinant CYP1A2 using cocktail of substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed