BDBM50596175 CHEMBL5192322

SMILES Fc1cncc(c1)-n1ccc(NC(=O)C2(CC2)c2ccc(cc2)C#N)n1

InChI Key InChIKey=CORIHHKUEFAUFT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50596175   

TargetElongation of very long chain fatty acids protein 1(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50596175(CHEMBL5192322)
Affinity DataIC50:  110nMAssay Description:Inhibition of ELOVL1 in human HEK2936E cells assessed as reduction of C26:0 LPC synthesis incubated for 48 hrs by cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetElongation of very long chain fatty acids protein 1(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50596175(CHEMBL5192322)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of ELOVL1 (unknown origin) using C22-acyl-CoA as substrate by radiometric enzyme assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed