BDBM50596293 CHEMBL5188658

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14C5=CC[C@H]2N(C)C(=O)\C=C\c1ccoc1)ccc3O

InChI Key InChIKey=RJGZNFKCKBWPCU-HEOWUMRYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50596293   

TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50596293(CHEMBL5188658)
Affinity DataKi:  0.0356nMAssay Description:Displacement of [3H]DPDPE from human KOR expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50596293(CHEMBL5188658)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50596293(CHEMBL5188658)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]U-69-593 from human DOR expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
University Of Tsukuba

Curated by ChEMBL
LigandPNGBDBM50596293(CHEMBL5188658)
Affinity DataKi:  31nMAssay Description:Binding affinity to OX1R (unknown origin) by calcium assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed