BDBM50596640 CHEMBL5194775

SMILES O=C(NC(=S)Nc1cccc2cccnc12)C12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=BBBBWEPMETWDGH-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50596640   

TargetP2X purinoceptor 7(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596640(CHEMBL5194775)
Affinity DataEC50:  6.62E+3nMAssay Description:Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596640(CHEMBL5194775)
Affinity DataEC50:  6.08E+3nMAssay Description:Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596640(CHEMBL5194775)
Affinity DataIC50:  73nMAssay Description:Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596640(CHEMBL5194775)
Affinity DataIC50:  68nMAssay Description:Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as reduction in ethidium bromide dye uptake p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50596640(CHEMBL5194775)
Affinity DataEC50:  2.19E+3nMAssay Description:Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed