BDBM50596640 CHEMBL5194775
SMILES O=C(NC(=S)Nc1cccc2cccnc12)C12CC3CC(CC(C3)C1)C2
InChI Key InChIKey=BBBBWEPMETWDGH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50596640
Affinity DataEC50: 6.62E+3nMAssay Description:Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
Affinity DataEC50: 6.08E+3nMAssay Description:Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair
Affinity DataIC50: 73nMAssay Description:Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx inc...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as reduction in ethidium bromide dye uptake p...More data for this Ligand-Target Pair
Affinity DataEC50: 2.19E+3nMAssay Description:Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ...More data for this Ligand-Target Pair