BDBM50596936 CHEMBL5170784

SMILES COc1ccc(C2NCCc3c2[nH]c2ccc(Cl)cc32)c(O)c1

InChI Key InChIKey=POCNIPUWZPJPSF-UHFFFAOYSA-N

Data  14 KI  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50596936   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  4.5nMAssay Description:Binding affinity to 5HT2B receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  8nMAssay Description:Binding affinity to 5HT7 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  32nMAssay Description:Binding affinity to 5HT1D receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  36nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  48nMAssay Description:Binding affinity to 5HT6 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  80nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  164nMAssay Description:Binding affinity to 5HT1B receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  177nMAssay Description:Binding affinity to 5HT5A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  225nMAssay Description:Binding affinity to 5HT2A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  609nMAssay Description:Binding affinity to D4 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  1.03E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  1.25E+3nMAssay Description:Binding affinity to D3 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  1.75E+3nMAssay Description:Binding affinity to 5HT1E receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataKi:  2.79E+3nMAssay Description:Binding affinity to 5HT3 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataEC50:  8.90nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataEC50:  8.30nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataEC50:  8.30nMAssay Description:Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50596936(CHEMBL5170784)
Affinity DataEC50:  8.90nMAssay Description:Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed