BDBM505974 6-(((S)-(6-fluoro-2- methylpyridin-3-yl)(1-((S)- 1-fluoropropan-2-yl)-1H-1,2,3-triazol-4- yl)methyl)amino)-4- (neopentylamino)quinoline- 3,8-dicarbonitrile::US11066414, Compound 623

SMILES C[C@@H](CF)N1NNC(=C1)[C@@H](Nc1cc(C#N)c2ncc(C#N)c(NCC(C)(C)C)c2c1)c1ccc(F)nc1C

InChI Key InChIKey=HVGAPXIMUJMFIG-OQRWROFFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 505974   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM505974(6-(((S)-(6-fluoro-2- methylpyridin-3-yl)(1-((S)- 1...)
Affinity DataIC50:  1nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent