BDBM50597471 CHEMBL5176687
SMILES COc1cccc(c1)[C@@H](C)NC(=O)c1ccc(nc1)-c1ccnc(F)c1
InChI Key InChIKey=HZBPSQIDFQPUKG-CYBMUJFWSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50597471
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Charles River Laboratories
Curated by ChEMBL
Charles River Laboratories
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human ROCK2 (5 to 554 residues) expressed in baculovirus infected Sf9 cells using S6K as substrate in...More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit gamma(Homo sapiens (Human))
Charles River Laboratories
Curated by ChEMBL
Charles River Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of PKA (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Time dependent inhibition of CYP1A2 in pooled human liver microsomes using midazolam as substrate preincubated for 30 mins in presence of NADPH follo...More data for this Ligand-Target Pair
TargetcGMP-dependent protein kinase 1(Homo sapiens (Human))
Charles River Laboratories
Curated by ChEMBL
Charles River Laboratories
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human PKG expressed in baculovirus infected Sf9 insect cells using RSK as substrate prein...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Charles River Laboratories
Curated by ChEMBL
Charles River Laboratories
Curated by ChEMBL
Affinity DataIC50: 9.26E+3nMAssay Description:Inhibition of AKT (unknown origin)More data for this Ligand-Target Pair