BDBM50597489 CHEMBL5208605
SMILES COc1cc(F)cc(c1)[C@@H](C)NC(=O)N1CCN(C[C@H]1C)c1ccncc1F
InChI Key InChIKey=XBIGUIIBZSJSRE-ZIAGYGMSSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50597489
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Charles River Laboratories
Curated by ChEMBL
Charles River Laboratories
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human ROCK2 (5 to 554 residues) expressed in baculovirus infected Sf9 cells using S6K as substrate in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Time dependent inhibition of CYP1A2 in pooled human liver microsomes using midazolam as substrate preincubated for 30 mins in presence of NADPH follo...More data for this Ligand-Target Pair
TargetcGMP-dependent protein kinase 1(Homo sapiens (Human))
Charles River Laboratories
Curated by ChEMBL
Charles River Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human PKG expressed in baculovirus infected Sf9 insect cells using RSK as substrate prein...More data for this Ligand-Target Pair