BDBM50597490 CHEMBL5199904

SMILES COc1cc(ccc1F)[C@@H](C)NC(=O)N1CCN(C[C@H]1C)c1ccncc1F

InChI Key InChIKey=DGRFHIHEGACPLB-ZIAGYGMSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50597490   

TargetcGMP-dependent protein kinase 1(Homo sapiens (Human))
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50597490(CHEMBL5199904)
Affinity DataIC50:  2.34E+3nMAssay Description:Inhibition of full length recombinant N-terminal GST-tagged human PKG expressed in baculovirus infected Sf9 insect cells using RSK as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Charles River Laboratories

Curated by ChEMBL
LigandPNGBDBM50597490(CHEMBL5199904)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human ROCK2 (5 to 554 residues) expressed in baculovirus infected Sf9 cells using S6K as substrate in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed