BDBM50597505 CHEMBL5174508

SMILES [I-].C[N+]1(CCOc2ccc(\C=C\c3ccccc3)cc2)CCC1

InChI Key InChIKey=KRRAWALNDVAFCJ-HRNDJLQDSA-M

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50597505   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50597505(CHEMBL5174508)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-epibatidine from human alpha4beta2 nAChR expressed in HEK293 cells membrane assessed as inhibition constant preincubated for 5 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50597505(CHEMBL5174508)
Affinity DataKi:  112nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR expressed in SH-SY5Y cells membrane assessed as inhibition constant preincubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50597505(CHEMBL5174508)
Affinity DataKi:  662nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nAChR expressed in SH-EP1 cells membrane assessed as inhibition constant preincubated for 5 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50597505(CHEMBL5174508)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50597505(CHEMBL5174508)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response treate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed