BDBM50597585 CHEMBL5176083

SMILES Fc1ccc2c(Cc3nnc(Cc4ccc(Cl)c(Cl)c4)n3CCCc3c[nH]cn3)c[nH]c2c1

InChI Key InChIKey=AYBQPLWOCHOTEZ-UHFFFAOYSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50597585   

TargetSomatostatin receptor type 4(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM50597585(CHEMBL5176083)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from human SST4 receptor expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 1(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM50597585(CHEMBL5176083)
Affinity DataKi:  873nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from SST1 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM50597585(CHEMBL5176083)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from human SST2A receptor expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 3(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM50597585(CHEMBL5176083)
Affinity DataKi:  1.56E+3nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from SST3 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 5(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM50597585(CHEMBL5176083)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from SST5 receptor (unknown origin) expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM50597585(CHEMBL5176083)
Affinity DataEC50:  1nMAssay Description:Agonist activity at recombinant human SST4 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed