BDBM50598266 CHEMBL5203652
SMILES CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(O)=O)NC(=O)COCCOCCNC(=O)c1ccc(c(c1)C(O)=O)-c1c2ccc(O)cc2oc2cc(=O)ccc12)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(O)=O)C(=O)NCCOCCOCC(=O)NCCCC[C@H](NC(=O)CNC(=O)[C@@H]1CSCC(=O)CSC[C@H](NC(=O)CN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N2CCC[C@H]2C(=O)N1)C(=O)NCC(N)=O
InChI Key InChIKey=FYWPIBWNEIANCT-BZHUYTBPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50598266
TargetKallikrein-5(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using B...More data for this Ligand-Target Pair
TargetKallikrein 1-related peptidase b5(Mus musculus)
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Ecole Polytechnique F�D�Rale De Lausanne (Epfl)
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Inhibition of mouse KLK5 assessed as inhibition constant using Boc-VPR-AMC as fluorogenic substrate incubated for 30 mins by fluorescence plate reade...More data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Inhibition of mouse KLK7 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKd: 119nMAssay Description:Binding affinity to human serum albumin by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 7.00E+3nMAssay Description:Binding affinity to mouse serum albumin by fluorescence polarization assayMore data for this Ligand-Target Pair