BDBM50598766 CHEMBL5170447

SMILES Cc1c(Cl)cccc1Nc1ccc(F)cc1C(=O)NCc1ccc(O)c(F)c1

InChI Key InChIKey=IZYDDEOSLGTSDZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50598766   

TargetDNA topoisomerase 1(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50598766(CHEMBL5170447)
Affinity DataIC50:  4.79E+3nMAssay Description:Inhibition of human topoisomerase I assessed as DNA relaxation using DNA pBR322 as substrate incubated for 30 mins by ethidium bromide staining based...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50598766(CHEMBL5170447)
Affinity DataIC50:  930nMAssay Description:Inhibition of human COX-2 assessed as by fluorescence based microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed