BDBM50600034 CHEMBL5194372
SMILES CC(C)S(=O)(=O)N1Cc2nc(nc(N3CCOCC3C)c2C1)-c1c[nH]c2ccccc12
InChI Key InChIKey=DLXAYOXMPQUZEL-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50600034
Affinity DataIC50: 136nMAssay Description:Inhibition of human full length recombinant mTOR in presence of [gamma-33P]ATP incubated for 40 mins by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 125nMAssay Description:Inhibition of human full length recombinant mTOR/FKBP12 in presence of [gamma-33P]ATP incubated for 40 mins by radiometric scintillation counting ana...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 9.44E+3nMAssay Description:Inhibition of human recombinant B-Raf (416 to end residues) using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mi...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 2.72E+3nMAssay Description:Inhibition of human PI3K-C2alpha (299 to ens residues) using phosphatidylinositol-4, 5-bisphosphate as substrate incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Sichuan University
Curated by ChEMBL
Sichuan University
Curated by ChEMBL
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of recombinant human full length PI3K p110delta/p85a using phosphatidylinositol-4, 5-bisphosphate as substrate incubated for 40 mins in pr...More data for this Ligand-Target Pair