BDBM50600517 CHEMBL5176835
SMILES NC(=O)c1cc2c(-c3ccc(s3)C(=O)NCc3ccccc3N)c(Cl)ccc2s1
InChI Key InChIKey=JLGZOWVGNXABBW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50600517
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Inhibition of human DYRK1A incubated for 90 mins in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataKi: 577nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of NanoLuc-fused human DYRK1A expressed in HEK293 cells using Nano-Glo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£
Curated by ChEMBL
Ach£
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of NanoLuc-fused human DYRK1B expressed in HEK293T cells using Nano-Glo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair