BDBM50600518 CHEMBL5191496

SMILES NC(=O)c1cc2c(cccc2s1)-c1ccc(s1)C(=O)NCc1cccc(N)c1

InChI Key InChIKey=SDZHQRUPXPKDOD-UHFFFAOYSA-N

Data  2 KI

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50600518   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Ach£

Curated by ChEMBL

LigandBDBM50600518(CHEMBL5191496)Copy SMILESCopy InChI

Affinity DataKi:  119nMAssay Description:Inhibition of human DYRK1A incubated for 90 mins in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails PubMed
Copy BDB DOI

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ach£

Curated by ChEMBL

LigandBDBM50600518(CHEMBL5191496)Copy SMILESCopy InChI

Affinity DataKi:  660nMAssay Description:Inhibition of human DYRK1B incubated for 130 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidPDB

In DepthDetails PubMed
Copy BDB DOI