BDBM50601172 CHEMBL5183104

SMILES CN1CC(c2ccc(cc2)S(=O)(=O)NCCOCCOCCNC(O)C(O)C(=O)NCCOCCOCCNS(=O)(=O)c2ccc(cc2)C2CN(C)Cc3c(Cl)cc(Cl)cc23)c2cc(Cl)cc(Cl)c2C1

InChI Key InChIKey=DPFILQZMXPDPFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50601172   

TargetSodium/hydrogen exchanger 3(Rattus norvegicus)
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601172(CHEMBL5183104)
Affinity DataIC50:  100nMAssay Description:Inhibition of rat NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibitor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium/hydrogen exchanger 3(Homo sapiens (Human))
Ardelyx

Curated by ChEMBL
LigandPNGBDBM50601172(CHEMBL5183104)
Affinity DataIC50:  4nMAssay Description:Inhibition of human NHE3 expressed in opossum kidney cells assessed as reduction in Na-HEPES buffer-mediated pH recovery in presence of NEH1 inhibito...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed