BDBM50602022 CHEMBL5197585

SMILES CC(C)(O)c1ccc(cc1)N1Cc2c(cc(nc2-c2ccccc2OCC(F)F)C2(C)COC2)C1=O

InChI Key InChIKey=ATZAIHIRNHQQLS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50602022   

TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602022(CHEMBL5197585)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602022(CHEMBL5197585)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed