BDBM50602284 CHEMBL4803149

SMILES COC(=O)c1ccc(CN2CCC(O)(Cn3cnc4c(-c5ccc(CN)cc5)n(C)nc4c3=O)CC2)c(Cl)c1

InChI Key InChIKey=AQZDRXXVFOYWHG-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50602284   

TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602284(CHEMBL4803149)
Affinity DataKd:  148nMAssay Description:Binding affinity to human USP7 (208 to 560 residues) by SPR methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50602284(CHEMBL4803149)
Affinity DataIC50:  61nMAssay Description:Inhibition of full-length USP7 (unknown origin) using ubiquitin-rhodamine 110 as substrate preincubated for 30 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB