BDBM50602317 CHEMBL5173962

SMILES C[C@H]1CN(C(=O)O1)c1cn2CCOc3cc(ccc3-c2n1)N1CCC[C@H]1C(N)=O

InChI Key InChIKey=AYTTVIUQQDMGRU-WFASDCNBSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50602317   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech

Curated by ChEMBL

LigandBDBM50602317(CHEMBL5173962)Copy SMILESCopy InChI

Affinity DataKi:  6.5nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2:3PS as substrate in presence of ATP measured after 120 mins by ADP-Glo assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails PubMed
Copy BDB DOI