BDBM50602926 CHEMBL5200160::US11814388, Compound 9

SMILES C(Oc1ccc(Nc2ncnc3[nH]ccc23)cc1)c1ccccc1

InChI Key InChIKey=GSVSRJBZRJBGOQ-UHFFFAOYSA-N

Data  2 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50602926   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Ferris State University

US Patent
LigandPNGBDBM50602926(CHEMBL5200160 | US11814388, Compound 9)
Affinity DataKd:  87nMAssay Description:Compounds 2-9 were evaluated in an ADP detection assay externally using the Kinomescan KdELECT platform from Discover X.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Ferris State University

US Patent
LigandPNGBDBM50602926(CHEMBL5200160 | US11814388, Compound 9)
Affinity DataKd:  680nMAssay Description:Compounds 2-9 were evaluated in an ADP detection assay externally using the Kinomescan KdELECT platform from Discover X.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTau-tubulin kinase 2(Homo sapiens (Human))
Csic

Curated by ChEMBL
LigandPNGBDBM50602926(CHEMBL5200160 | US11814388, Compound 9)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of recombinant human TTBK2 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ferris State University

US Patent
LigandPNGBDBM50602926(CHEMBL5200160 | US11814388, Compound 9)
Affinity DataKd:  9.80E+3nMAssay Description:Compounds 2-9 were evaluated in an ADP detection assay externally using the Kinomescan KdELECT platform from Discover X.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTau-tubulin kinase 1(Homo sapiens (Human))
Csic

Curated by ChEMBL
LigandPNGBDBM50602926(CHEMBL5200160 | US11814388, Compound 9)
Affinity DataIC50:  750nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAurora kinase A(Homo sapiens (Human))
Ferris State University

US Patent
LigandPNGBDBM50602926(CHEMBL5200160 | US11814388, Compound 9)
Affinity DataKd: >3.00E+4nMAssay Description:Compounds 2-9 were evaluated in an ADP detection assay externally using the Kinomescan KdELECT platform from Discover X.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent