BDBM50602926 CHEMBL5200160::US11814388, Compound 9
SMILES C(Oc1ccc(Nc2ncnc3[nH]ccc23)cc1)c1ccccc1
InChI Key InChIKey=GSVSRJBZRJBGOQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50602926
Affinity DataKd: 87nMAssay Description:Compounds 2-9 were evaluated in an ADP detection assay externally using the Kinomescan KdELECT platform from Discover X.More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Ferris State University
US Patent
Ferris State University
US Patent
Affinity DataKd: 680nMAssay Description:Compounds 2-9 were evaluated in an ADP detection assay externally using the Kinomescan KdELECT platform from Discover X.More data for this Ligand-Target Pair
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of recombinant human TTBK2 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataKd: 9.80E+3nMAssay Description:Compounds 2-9 were evaluated in an ADP detection assay externally using the Kinomescan KdELECT platform from Discover X.More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Inhibition of recombinant human TTBK1 using RICDLHDDEEDEAMSITA as substrate incubated for 30 mins in presence of 33P-gamma-ATPMore data for this Ligand-Target Pair
Affinity DataKd: >3.00E+4nMAssay Description:Compounds 2-9 were evaluated in an ADP detection assay externally using the Kinomescan KdELECT platform from Discover X.More data for this Ligand-Target Pair