BDBM50603512 CHEMBL5177475

SMILES CC(C)N(Cc1ccc(cc1)C(=O)NO)S(=O)(=O)c1cc(F)c(F)c(F)c1F

InChI Key InChIKey=SJWJGLIJTRUXIZ-UHFFFAOYSA-N

Data  1 KI  11 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50603512   

TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataKi:  4.10nMAssay Description:Binding affinity to full length human recombinant HDAC6 expressed in Sf9 baculovirus system assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50:  6nMAssay Description:Inhibition of full length human recombinant HDAC6 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC8 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC11 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC10 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50:  316nMAssay Description:Inhibition of full length human recombinant HDAC2 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC4 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC5 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC7 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC9 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC3 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50603512(CHEMBL5177475)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of full length human recombinant HDAC1 expressed in Sf9 baculovirus system using FAM-labeled acetylated peptide as substrate by measuring ...More data for this Ligand-Target Pair
In DepthDetails PubMed