BDBM50603930 CHEMBL5174650::US11873292, Compound A54

SMILES CCCC(=O)N1CCc2cc(ccc12)C1CC1NCC1CCNCC1

InChI Key InChIKey=ZRQRSRLEWGEPTB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50603930   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50603930(CHEMBL5174650 | US11873292, Compound A54)
Affinity DataIC50:  15.6nMAssay Description:Principle: LSD1 specifically removes the methylation modification at K4 lysine on H3 polypeptide substrate, making it a substrate without methylation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50603930(CHEMBL5174650 | US11873292, Compound A54)
Affinity DataIC50: >1.00E+5nMAssay Description:Principle: A specific luciferin derivative was used as a substrate. MAOA or MAOB can catalyze the conversion of substrate to luciferin methyl ester. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50603930(CHEMBL5174650 | US11873292, Compound A54)
Affinity DataIC50: >1.00E+5nMAssay Description:Principle: A specific luciferin derivative was used as a substrate. MAOA or MAOB can catalyze the conversion of substrate to luciferin methyl ester. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50603930(CHEMBL5174650 | US11873292, Compound A54)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using luminogenic MAO substrate incubated for 1 hr by lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific histone demethylase 2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50603930(CHEMBL5174650 | US11873292, Compound A54)
Affinity DataIC50:  3.95E+3nMAssay Description:Inhibition of recombinant human full length LSD2 using biotinylated H3K4Me2 peptide as substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50603930(CHEMBL5174650 | US11873292, Compound A54)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using luminogenic MAO substrate incubated for 1 hr by lucife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50603930(CHEMBL5174650 | US11873292, Compound A54)
Affinity DataIC50:  1.56E+4nMAssay Description:Inhibition of N-terminal His/GST-tagged human LSD1 (172 to 852 residues) expressed in expressed in baculovirus infected insect cells using biotinylat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed