BDBM50603930 CHEMBL5174650::US11873292, Compound A54
SMILES CCCC(=O)N1CCc2cc(ccc12)C1CC1NCC1CCNCC1
InChI Key InChIKey=ZRQRSRLEWGEPTB-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50603930
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Shanghai Institute of Materia Medica
US Patent
Shanghai Institute of Materia Medica
US Patent
Affinity DataIC50: 15.6nMAssay Description:Principle: LSD1 specifically removes the methylation modification at K4 lysine on H3 polypeptide substrate, making it a substrate without methylation...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Shanghai Institute of Materia Medica
US Patent
Shanghai Institute of Materia Medica
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:Principle: A specific luciferin derivative was used as a substrate. MAOA or MAOB can catalyze the conversion of substrate to luciferin methyl ester. ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Shanghai Institute of Materia Medica
US Patent
Shanghai Institute of Materia Medica
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:Principle: A specific luciferin derivative was used as a substrate. MAOA or MAOB can catalyze the conversion of substrate to luciferin methyl ester. ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Shanghai Institute of Materia Medica
US Patent
Shanghai Institute of Materia Medica
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using luminogenic MAO substrate incubated for 1 hr by lucife...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Shanghai Institute Of Materia Medica
Curated by ChEMBL
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of recombinant human full length LSD2 using biotinylated H3K4Me2 peptide as substrate by TR-FRET assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Shanghai Institute of Materia Medica
US Patent
Shanghai Institute of Materia Medica
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using luminogenic MAO substrate incubated for 1 hr by lucife...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Shanghai Institute of Materia Medica
US Patent
Shanghai Institute of Materia Medica
US Patent
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of N-terminal His/GST-tagged human LSD1 (172 to 852 residues) expressed in expressed in baculovirus infected insect cells using biotinylat...More data for this Ligand-Target Pair