BDBM50604027 CHEMBL5184634::US20230312529, Compound 6i

SMILES CCN1CCN(CC1)c1ccc(Nc2ncc(C)c(Nc3ccc4cn[nH]c4c3)n2)cc1OC

InChI Key InChIKey=PQIKUMYNSRASMV-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50604027   

TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Wenzhou Medical University

US Patent
LigandPNGBDBM50604027(CHEMBL5184634 | US20230312529, Compound 6i)
Affinity DataIC50:  2.70nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Wenzhou Medical University

US Patent
LigandPNGBDBM50604027(CHEMBL5184634 | US20230312529, Compound 6i)
Affinity DataIC50:  1.70nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Wenzhou Medical University

US Patent
LigandPNGBDBM50604027(CHEMBL5184634 | US20230312529, Compound 6i)
Affinity DataIC50:  27nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Wenzhou Medical University

US Patent
LigandPNGBDBM50604027(CHEMBL5184634 | US20230312529, Compound 6i)
Affinity DataIC50:  2.70nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Wenzhou Medical University

US Patent
LigandPNGBDBM50604027(CHEMBL5184634 | US20230312529, Compound 6i)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Wenzhou Medical University

US Patent
LigandPNGBDBM50604027(CHEMBL5184634 | US20230312529, Compound 6i)
Affinity DataIC50:  5nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Wenzhou Medical University

US Patent
LigandPNGBDBM50604027(CHEMBL5184634 | US20230312529, Compound 6i)
Affinity DataIC50:  7.70nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Wenzhou Medical University

US Patent
LigandPNGBDBM50604027(CHEMBL5184634 | US20230312529, Compound 6i)
Affinity DataIC50:  694nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Wenzhou Medical University

US Patent
LigandPNGBDBM50604027(CHEMBL5184634 | US20230312529, Compound 6i)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Wenzhou Medical University

US Patent
LigandPNGBDBM50604027(CHEMBL5184634 | US20230312529, Compound 6i)
Affinity DataIC50:  1.70nMAssay Description:The method adopted in the test was Caliper Mobility Shift Assay, which was a detection platform based on the mobility detection technology of microfl...More data for this Ligand-Target Pair
In DepthDetails US Patent