BDBM50604567 CHEMBL5171798

SMILES CC(=O)Nc1ccc(Nc2ncnc(N[C@@H](C3CCCCC3)C(=O)OC(C)(C)C)n2)cc1

InChI Key InChIKey=HXRVHSQMEQCPJZ-IBGZPJMESA-N

Data  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50604567   

TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50604567(CHEMBL5171798)
Affinity DataEC50:  3.27E+5nMAssay Description:Displacement of Flu-P19 probe from human NPR-C (27 to 541 residues) by fluorescence polarization analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50604567(CHEMBL5171798)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAtrial natriuretic peptide receptor 3(Rattus norvegicus)
University College London

Curated by ChEMBL
LigandPNGBDBM50604567(CHEMBL5171798)
Affinity DataEC50:  6.24E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed