BDBM50604614 CHEMBL5172345

SMILES CCc1ncc([nH]1)-c1cc2c(o1)c(cn(C)c2=O)-c1cc(NS(=O)(=O)CC)ccc1Oc1ccc(F)cc1F

InChI Key InChIKey=MJVRZRYHZKAUFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50604614   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50604614(CHEMBL5172345)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of C-terminal His6-tagged BRD4 BD2 (unknown origin) using H-YSGRGK(Ac)GGK(Ac)GLGK(Ac)-GGAK(Ac)RHRK-Biotin-OH as substrate incubated for 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50604614(CHEMBL5172345)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of C-terminal His6-tagged BRD4 BD1 (unknown origin) using H-YSGRGK(Ac)GGK(Ac)GLGK(Ac)-GGAK(Ac)RHRK-Biotin-OH as substrate incubated for 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed