BDBM50604625 CHEMBL5204783
SMILES Cc1cc(F)cc(C)c1Oc1ccc(cc1-c1cn(C)c(=O)c2cc(oc12)-c1cnc([nH]1)C1CCCCC1)C(C)(C)O
InChI Key InChIKey=UCJMBWXOKLINTN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50604625
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 326nMAssay Description:Inhibition of C-terminal His6-tagged BRD4 BD1 (unknown origin) using H-YSGRGK(Ac)GGK(Ac)GLGK(Ac)-GGAK(Ac)RHRK-Biotin-OH as substrate incubated for 1 ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of C-terminal His6-tagged BRD4 BD2 (unknown origin) using H-YSGRGK(Ac)GGK(Ac)GLGK(Ac)-GGAK(Ac)RHRK-Biotin-OH as substrate incubated for 1 ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of C-terminal His6-tagged BRD3 BD2 (unknown origin) using H-YSGRGK(Ac)GGK(Ac)GLGK(Ac)-GGAK(Ac)RHRK-Biotin-OH as substrate incubated for 1 ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of C-terminal His6-tagged BRD2 BD2 (unknown origin) using H-YSGRGK(Ac)GGK(Ac)GLGK(Ac)-GGAK(Ac)RHRK-Biotin-OH as substrate incubated for 1 ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 4.96E+3nMAssay Description:Binding affinity to His6-fused BRD4 BD1 (unknown origin) assessed as dissociation constant in PBS incubated for 1 hrs by biolayer interferometry anal...More data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 195nMAssay Description:Binding affinity to His6-fused BRDT BD2 (unknown origin) assessed as dissociation constant in PBS incubated for 1 hrs by biolayer interferometry anal...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 9.78E+3nMAssay Description:Binding affinity to His6-fused human BRD3 BD1 assessed as dissociation constant in PBS incubated for 1 hrs by biolayer interferometry analysisMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 90nMAssay Description:Binding affinity to His6-fused BRD3 BD2 (unknown origin) assessed as dissociation constant in PBS incubated for 1 hrs by biolayer interferometry anal...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 1.07E+3nMAssay Description:Binding affinity to His6-fused BRD2 BD1 (unknown origin) assessed as dissociation constant in PBS incubated for 1 hrs by biolayer interferometry anal...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 126nMAssay Description:Binding affinity to His6-fused BRD2 BD2 (unknown origin) assessed as dissociation constant in PBS incubated for 1 hrs by biolayer interferometry anal...More data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 3.31E+3nMAssay Description:Binding affinity to His6-fused BRDT BD1 (unknown origin) assessed as dissociation constant in PBS incubated for 1 hrs by biolayer interferometry anal...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 44nMAssay Description:Binding affinity to His6-fused BRD4 BD2 (unknown origin) assessed as dissociation constant in PBS incubated for 1 hrs by biolayer interferometry anal...More data for this Ligand-Target Pair