BDBM50604885 CHEMBL5177177
SMILES Fc1cccc(c1)-c1ccc2c(N3CCN(CC3)C(=O)C=C)n(Cc3ccccc3)nc2c1
InChI Key InChIKey=BPENEDJSHAUQGD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50604885
Affinity DataKi: 410nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia co...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Yancheng Teachers University
Curated by ChEMBL
Yancheng Teachers University
Curated by ChEMBL
Affinity DataKi: 1.11E+5nMAssay Description:Displacement of fluorescein tagged BID BH3 peptide from human MCL-1 (172 to 327 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibi...More data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-3(Homo sapiens)
Yancheng Teachers University
Curated by ChEMBL
Yancheng Teachers University
Curated by ChEMBL
Affinity DataKi: >4.00E+5nMAssay Description:Displacement of FAM- labeled YAP1 peptide from TEAD4 (217 to 434 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhi...More data for this Ligand-Target Pair
Affinity DataKi: >4.00E+5nMAssay Description:Displacement of fluorescein tagged BAK peptide from N-terminal His tagged human BCL-xL (1 to 209 residues) expressed in Escherichia coli BL21 (DE3) a...More data for this Ligand-Target Pair
Affinity DataKi: >4.00E+5nMAssay Description:Displacement of fluorescein tagged BIM peptide from N-terminal His tagged human BCL-2 (1 to 170 residues) expressed in Escherichia coli BL21 (DE3) as...More data for this Ligand-Target Pair
TargetTranscriptional enhancer factor TEF-4(Homo sapiens)
Yancheng Teachers University
Curated by ChEMBL
Yancheng Teachers University
Curated by ChEMBL
Affinity DataKi: >4.00E+5nMAssay Description:Displacement of FAM- labeled YAP1 peptide from TEAD2 (217 to 447 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhi...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Homo sapiens)
Yancheng Teachers University
Curated by ChEMBL
Yancheng Teachers University
Curated by ChEMBL
Affinity DataKi: >4.00E+5nMAssay Description:Inhibition of biotinylated tagged PD-1 (unknown origin)/His tagged PD-L1 (unknown origin) protein-protein interaction assessed as inhibition constant...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Yancheng Teachers University
Curated by ChEMBL
Yancheng Teachers University
Curated by ChEMBL
Affinity DataKi: >4.00E+5nMAssay Description:Displacement of FAM- labeled PDI peptide from MDM2 (1 to 118 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhibiti...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Yancheng Teachers University
Curated by ChEMBL
Yancheng Teachers University
Curated by ChEMBL
Affinity DataKi: >4.00E+5nMAssay Description:Binding affinity to recombinant human BRD2 BD1 (72-205 residues) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 2(Homo sapiens (Human))
Yancheng Teachers University
Curated by ChEMBL
Yancheng Teachers University
Curated by ChEMBL
Affinity DataKi: >4.00E+5nMAssay Description:Binding affinity to recombinant human BRD2 BD2 (349-460 residues) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Yancheng Teachers University
Curated by ChEMBL
Yancheng Teachers University
Curated by ChEMBL
Affinity DataKi: >4.00E+5nMAssay Description:Binding affinity to recombinant human BRD3 BD1 (24-144 residues) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 3(Homo sapiens (Human))
Yancheng Teachers University
Curated by ChEMBL
Yancheng Teachers University
Curated by ChEMBL
Affinity DataKi: >4.00E+5nMAssay Description:Binding affinity to recombinant human BRD3 BD2 (306-417 residues) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: >4.00E+5nMAssay Description:Inhibition of N-terminal biotinylated human BCL9 (350 to 375 residues)/C-terminal 6-His-tagged beta-catenin (1 to 781 residues) (unknown origin) expr...More data for this Ligand-Target Pair
Affinity DataKd: 262nMAssay Description:Binding affinity to His-tagged recombinant BFL-1 (1 to 151 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as dissociati...More data for this Ligand-Target Pair