BDBM50605782 CHEMBL5174953

SMILES C[C@H]1CCC[C@@H](C)N1c1nnc2ccc(O[C@@H]3CC[C@H](NC(=O)Nc4cc(nn4-c4cnn(CCN(C)C)c4)C(C)(C)C)c4ccccc34)cn12

InChI Key InChIKey=NEOFBONIFALDKM-MAOWDPDTSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50605782   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50605782(CHEMBL5174953)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of human recombinant full length GST-tagged p38alpha expressed in Escherichia coli preincubated for 2 hrs followed by ATP addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50605782(CHEMBL5174953)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human full length His-tagged p38delta expressed in baculovirus expression system preincubated for 2 hrs followed by ATP add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 12(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50605782(CHEMBL5174953)
Affinity DataIC50:  805nMAssay Description:Inhibition of recombinant human full length His-tagged p38gamma expressed in baculovirus expression system preincubated for 2 hrs followed by ATP add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50605782(CHEMBL5174953)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of recombinant human full length His-tagged p38beta expressed in baculovirus expression system preincubated for 2 hrs followed by ATP addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed