BDBM50605877 CHEMBL5176939

SMILES Cc1onc(c1COc1ccc2C(=O)N(Cc3ccno3)CCc2n1)-c1ccc(F)cc1

InChI Key InChIKey=MZDDWNYMFDVWOJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50605877   

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605877(CHEMBL5176939)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605877(CHEMBL5176939)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed