BDBM50606492 CHEMBL5218797
SMILES CCC(=O)Nc1cccc(c1)-c1c([nH]c2ncn(C3CCCCC3)c(=O)c12)-c1ccc(cc1)N1CCN(C)CC1
InChI Key InChIKey=PAGLOCXKPUTYNO-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50606492
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangxi Science & Technology Normal University
Curated by ChEMBL
Jiangxi Science & Technology Normal University
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human wild type GST-tagged EGFR expressed in Sf9 cells assessed as substrate phosphorylation using TK-peptide as substrate incubated fo...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangxi Science & Technology Normal University
Curated by ChEMBL
Jiangxi Science & Technology Normal University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of human GST-tagged EGFR L858R/T790M/C797S mutant expressed in Sf9 cells assessed as substrate phosphorylation using TK-peptide as substra...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangxi Science & Technology Normal University
Curated by ChEMBL
Jiangxi Science & Technology Normal University
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human GST-tagged EGFR L858R/T790M mutant expressed in Sf9 cells assessed as substrate phosphorylation using TK-peptide as substrate inc...More data for this Ligand-Target Pair