BDBM50606495 CHEMBL5220529

SMILES CCC(=O)Nc1cccc(c1)-c1c([nH]c2ncnc(OCC(C)C)c12)-c1ccc(cc1)N1CCN(C)CC1

InChI Key InChIKey=GYFHWHMKICJOJM-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50606495   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50606495(CHEMBL5220529)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human wild type GST-tagged EGFR expressed in Sf9 cells assessed as substrate phosphorylation using TK-peptide as substrate incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50606495(CHEMBL5220529)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human GST-tagged EGFR L858R/T790M/C797S mutant expressed in Sf9 cells assessed as substrate phosphorylation using TK-peptide as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50606495(CHEMBL5220529)
Affinity DataIC50: <0.100nMAssay Description:Inhibition of human GST-tagged EGFR L858R/T790M mutant expressed in Sf9 cells assessed as substrate phosphorylation using TK-peptide as substrate inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB