BDBM50606497 CHEMBL5218879

SMILES OCCCCc1ccc(cc1)-c1nc(c([nH]1)-c1ccnc2NC(Cc12)c1ccccc1)-c1ccc(F)cc1

InChI Key InChIKey=IIEIOLNIDXMMAS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50606497   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50606497(CHEMBL5218879)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50606497(CHEMBL5218879)
Affinity DataIC50: <0.300nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50606497(CHEMBL5218879)
Affinity DataIC50:  8.40nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed