BDBM50607 (E)-1-(4-Hydroxy-phenyl)-3-pyridin-3-yl-propenone::(E)-1-(4-hydroxyphenyl)-3-(3-pyridinyl)-2-propen-1-one::(E)-1-(4-hydroxyphenyl)-3-(3-pyridyl)prop-2-en-1-one::(E)-1-(4-hydroxyphenyl)-3-pyridin-3-yl-prop-2-en-1-one::(E)-1-(4-hydroxyphenyl)-3-pyridin-3-ylprop-2-en-1-one::CA standard inhibitor, 1::MLS000778012::SMR000414406::cid_5920835
SMILES Oc1ccc(cc1)C(=O)\C=C\c1cccnc1
InChI Key InChIKey=JRNSRWHZOUBRQN-FPYGCLRLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50607
Affinity DataKi: 780nM ΔG°: -8.33kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Affinity DataKi: 1.25E+4nM ΔG°: -6.68kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Affinity DataKi: 7.65E+4nM ΔG°: -5.61kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University
Curated by PubChem BioAssay
Emory University
Curated by PubChem BioAssay
Affinity DataIC50: 5.40E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair