BDBM50607288 CHEMBL5220817

SMILES Cc1ccccc1Oc1cc(c(F)cc1C#N)-n1c(=O)cc([nH]c1=O)C(F)(F)F

InChI Key InChIKey=QAJPTKHORNTZSQ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607288   

TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50607288(CHEMBL5220817)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50607288(CHEMBL5220817)
Affinity DataIC50:  554nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB