BDBM50607310 CHEMBL5220057

SMILES COc1cc(Cl)c(Oc2ccccc2C)cc1-n1c(=O)cc([nH]c1=O)C(F)(F)F

InChI Key InChIKey=BYUTZQUXYNGRJD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50607310   

TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50607310(CHEMBL5220057)
Affinity DataIC50:  4.33E+3nMAssay Description:Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50607310(CHEMBL5220057)
Affinity DataIC50:  438nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed