BDBM50607314 CHEMBL5219349
SMILES Cc1ccccc1Oc1cc(-n2c(=O)cc([nH]c2=O)C(F)(F)F)c2ccccc2c1C#N
InChI Key InChIKey=JBKRLZPXWNTYBD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50607314
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Bayer Pharma
Curated by ChEMBL
Bayer Pharma
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in ...More data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Bayer Pharma
Curated by ChEMBL
Bayer Pharma
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in ...More data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Bayer Pharma
Curated by ChEMBL
Bayer Pharma
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assayMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Bayer Pharma
Curated by ChEMBL
Bayer Pharma
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assayMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Bayer Pharma
Curated by ChEMBL
Bayer Pharma
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assayMore data for this Ligand-Target Pair
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Bayer Pharma
Curated by ChEMBL
Bayer Pharma
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in ...More data for this Ligand-Target Pair