BDBM50607316 CHEMBL5219436

SMILES Cc1ccccc1Oc1cc(-n2c(=O)cc([nH]c2=O)C(F)(F)c2ccccc2)c2ccccc2c1Cl

InChI Key InChIKey=ORZQWCVWJWOYDJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50607316   

TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50607316(CHEMBL5219436)
Affinity DataIC50:  200nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50607316(CHEMBL5219436)
Affinity DataIC50:  200nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50607316(CHEMBL5219436)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50607316(CHEMBL5219436)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBranched-chain-amino-acid aminotransferase, mitochondrial(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50607316(CHEMBL5219436)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant BCAT2 using leucine and alpha-KG as substrate in presence of NADH by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetBranched-chain-amino-acid aminotransferase, cytosolic(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50607316(CHEMBL5219436)
Affinity DataIC50:  180nMAssay Description:Inhibition of N-terminal his-tagged human recombinant BCAT1 expressed in Escherichia coli BL21(DE3) cells using leucine and alpha-KG as substrate in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed